Defend
Defend
Cleanse biofilm & support bladder wall integrity.
- 60-Day Money-Back Guarantee
- FSA/HSA eligible
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Customer Support
Discreet Packaging
Lemonade Flavor
Vegan
Antibiotic-free
Gluten-free









Why the Complete Regimen?
The Complete Regimen features our 3 essential, proactive products in one convenient bundle—our most popular choice. Each product is designed to serve a unique purpose, working together to provide comprehensive support. Flush, our drink mix,when taken daily, is an effective, easy way to flush your urinary tract. Defend cleanses biofilm and supports bladder wall integrity. Promote, our clinically studied vaginal probiotic blend, supports your vaginal health. †
Why Defend?
Defend is one part of our 3-part proactive regimen, recommended for anyone impacted by urinary health 3 times or more a year. Defend cleanses biofilm, which helps to keep the urinary tract clear on a day-to-day basis. It also supports bladder wall integrity. You can take Defend by itself, but we recommend everyone looking for better urinary health also take Flush (our drink mix).
All about Defend

How it works
- Mechanism research on the ingredients in Defend shows their ability to cleanse biofilm. Defend also supports bladder wall integrity. With these two functions, Defend helps to keep your bladder clean in the face of hard-to-pinpoint things like stress, hormonal changes and holding your bladder.
Directions
- Each bottle includes a 1-month supply (60 capsules). Take 2 capsules together with water daily.
What is biofilm?
- Biofilm is a collection of microorganisms bound together that attaches to surfaces, like the bladder wall. Mechanism research on the ingredients in Defend shows their ability to clean biofilm.
Defend's science and ingredients

Black Pepper Powder
Piperine is the “active” compound in black pepper. Oddly enough, Piperine can increase the bioavailability of curcumin by 2,000%! Typically, curcumin has poor bioavailability, meaning our bodies don’t absorb the ingredient well on its own. Voolast Defend includes black pepper powder in a small dose to enable our bodies to better absorb curcumin.
D-Mannose
D-Mannose is a type of carbohydrate that occurs naturally in small quantities in many fruits and vegetables including apples, peaches, green beans, and broccoli. D-Mannose is an important part of human metabolism and urinary health. It has been shown to bind to microorganisms and flushes them from the urinary tract.
Green Tea Leaf Extract
This extract is mostly (95%) made up of micronutrients in green tea leaves called catechins, like EGCG and EGC. These have been the subject of much research on various health benefits and have antioxidant properties. Along with curcumin, catechins have been shown to cleanse biofilm in preliminary laboratory research. The green tea extract in Voolast Defend is from the leaves of green tea plants.
Turmeric Root Extract
Turmeric Root Extract (95% Curcuminoids) is the “active” compound in turmeric, a flowering plant commonly used as a spice that is a member of the ginger family. Turmeric Root Extract gives Voolast Defend its yellowish color. Biofilm can build-up in the urinary tract and turmeric root extract (along with the polyphenols from green tea) has been shown to cleanse biofilm in preliminary laboratory research. The curcumin in Voolast Defend is extracted from the turmeric root.
We recommend talking with your physician if you’re pregnant, nursing, take blood thinners or have a history of liver or gallbladder issues. If you take blood thinners, curcumin, an ingredient in Defend, may cause additional blood thinning. Stop use and see your physician if you develop symptoms of liver problems, such as fatigue, jaundice, and dark urine.
Vitamin D3
42% of all adults in the U.S. are Vitamin D deficient. The vitamin D in Defend is vitamin D3, also called cholecalciferol, the form of vitamin D made by the skin when exposed to sunlight. New research shows that Vitamin D supplementation increases tight junction proteins in the bladder. Essentially, these proteins connect cells that are next to each other.
Other ingredients
Provides Defend's capsule and consistency
Hypromellose – This is a vegetarian polymer used to make the capsule.
Rice Flour – This is used to keep the space packed tightly to secure the ingredients.
Magnesium Stearate – This is a common ingredient in food and supplements to safely keep powders from clumping.
Silica – Also known as silicon dioxide, silica is one of the most common compounds on earth and is found in many plants. Commonly used in food products, in Voolast Defend, silica safely maintains the powder’s texture and keeps it from clumping together.
Common questions about Defend

Can I take Defend alongside the other products (Flush and Promote)
Yes, Defend, Flush and Promote, are meant to be taken together. All together, these products make up our Complete Regimen - our most popular product bundle. Taking all three products together provides you maximum urinary support. Flush (our drink mix) flushes the urinary tract, Defend cleanses biofilm from the urinary tract and supports bladder wall integrity, and Promote helps maintain healthy vaginal bacteria. Get the Complete Regimen
Does Voolast have caffeine in it?
Green tea leaf extract is an ingredient in Defend, but the caffeine is removed during the extraction process, leaving only a small amount. This small amount is unlikely to have a stimulating effect, but individuals who are highly sensitive to caffeine may prefer to take Defend earlier in the day.
How do I know if Defend is right for me?
Defend is one part of our 3-part proactive regimen. It’s designed to keep the urinary tract clear on a day-to-day basis by regularly cleansing biofilm, and it also supports bladder wall integrity. You can take Defend by itself, but we recommend that everyone looking for better urinary health also take Flush (our drink mix).
How is Defend different from Flush?
Defend and Flush contain different active ingredients. While the two products are complementary, they don’t have the same function. Defend is designed to keep the urinary tract clear on a day-to-day basis by regularly cleansing biofilm, and supporting bladder wall integrity. Flush (our drink mix) flushes the urinary tract when you need support, like after sex, with the right amount of effective ingredients. For more support, we recommend bundling the two
Is it vegan?
Voolast Defend is not vegan because the vitamin D is sourced from sheep's wool. We chose this source because it is the same version used in clinical research, and we wanted to ensure the maximum efficacy. We apologize for how this may affect our vegan customers.
What if I'm already taking Vitamin D?
The recommended daily upper limit for vitamin D is 4000 IU. Most vitamin D supplements have <2000 IU, and Voolast Defend now includes 1500 IU. So, most people should be in the clear, but if you are currently taking other vitamin D sources be sure to check the volume. We've included that amount to be close to the clinical research amounts but not have a full 2000 IU in case people are supplementing with vitamin D that goes up to 2000 IU to stay at a lower dosage of 3,500 per day.
What is biofilm?
Biofilm is a collection of microorganisms bound together that attaches to surfaces, like the bladder wall. Mechanism research on the ingredients in Defend shows their ability to clean biofilm.
Why are Voolast Defend capsules orange?
The orange color you're seeing is curcumin powder, one of the ingredients in Defend. Due to the natural properties of curcumin, slight color variations can occur from month to month — this is completely normal!
Our refund policy
Your well being is our #1 priority. If Voolast doesn’t work for you, we’ll give you your money back.
And we promise our customer success team will make it easy. We pride ourselves on having a responsive, caring team full of real people ready to answer all your questions and help in any way.

From our founder: I had 8 UTIs in one year…
“I was stuck in the cycle of UTIs for years. I was desperate for a way to get ahead, but was told there was little I could do. This inspired my husband and I to start Voolast, alongside doctors & scientists. Now, we’ve been able to help over 500,000 people and counting. Ready to give us a try?”